Effects of cryopreservation on lymphocyte immunophenotype and function
A Costantini, S Mancini, S Giuliodoro, L Butini… - Journal of …, 2003 - Elsevier
Cryopreservation of isolated peripheral blood mononuclear cells (PBMCs) for phenotypic
and functional analyses is considered a standard procedure in order to minimize operator-
dependent inter-assay variability and to optimize the use of available resources. However,
only few and somewhat conflicting data are presently available on the effects of
cryopreservation on PBMCs, especially in samples from HIV-infected patients in which
assessment of lymphocyte phenotype and function is of the outmost importance. In this …
and functional analyses is considered a standard procedure in order to minimize operator-
dependent inter-assay variability and to optimize the use of available resources. However,
only few and somewhat conflicting data are presently available on the effects of
cryopreservation on PBMCs, especially in samples from HIV-infected patients in which
assessment of lymphocyte phenotype and function is of the outmost importance. In this …
