Survival after shock requiring high-dose vasopressor therapy
SM Brown, MJ Lanspa, JP Jones, KG Kuttler, Y Li… - Chest, 2013 - Elsevier
Background Some patients with hypotensive shock do not respond to usual doses of
vasopressor therapy. Very little is known about outcomes after high-dose vasopressor
therapy (HDV). We sought to characterize survival among patients with shock requiring
HDV. We also evaluated the possible utility of stress-dose corticosteroid therapy in these
patients. Methods We conducted a retrospective study of patients with shock requiring HDV
in the ICUs of five hospitals from 2005 through 2010. We defined HDV as receipt at any point …
vasopressor therapy. Very little is known about outcomes after high-dose vasopressor
therapy (HDV). We sought to characterize survival among patients with shock requiring
HDV. We also evaluated the possible utility of stress-dose corticosteroid therapy in these
patients. Methods We conducted a retrospective study of patients with shock requiring HDV
in the ICUs of five hospitals from 2005 through 2010. We defined HDV as receipt at any point …