Podometrics as a potential clinical tool for glomerular disease management
M Kikuchi, L Wickman, JB Hodgin, RC Wiggins - Seminars in nephrology, 2015 - Elsevier
Chronic kidney disease culminating in end-stage kidney disease is a major public health
problem costing in excess of $40 billion per year with high morbidity and mortality. Current
tools for glomerular disease monitoring lack precision and contribute to poor outcome. The
podocyte depletion hypothesis describes the major mechanisms underlying the progression
of glomerular diseases, which are responsible for more than 80% of cases of end-stage
kidney disease. The question arises of whether this new knowledge can be used to improve …
problem costing in excess of $40 billion per year with high morbidity and mortality. Current
tools for glomerular disease monitoring lack precision and contribute to poor outcome. The
podocyte depletion hypothesis describes the major mechanisms underlying the progression
of glomerular diseases, which are responsible for more than 80% of cases of end-stage
kidney disease. The question arises of whether this new knowledge can be used to improve …