Membrane complement regulatory proteins
DD Kim, WC Song - Clinical immunology, 2006 - Elsevier
A number of proteins anchored on the cell surface function to protect host tissues from
bystander injury when complement is activated. In humans, they include decay-accelerating
factor (DAF, CD55), membrane cofactor protein (MCP, CD46), complement receptor 1 (CR1,
CD35) and CD59. Although disease conditions directly attributable to abnormal function of
these proteins are relatively rare, it has become evident from recent studies using animal
models that membrane complement regulatory proteins are important modulators of tissue …
bystander injury when complement is activated. In humans, they include decay-accelerating
factor (DAF, CD55), membrane cofactor protein (MCP, CD46), complement receptor 1 (CR1,
CD35) and CD59. Although disease conditions directly attributable to abnormal function of
these proteins are relatively rare, it has become evident from recent studies using animal
models that membrane complement regulatory proteins are important modulators of tissue …