[HTML][HTML] Human immunodeficiency virus and the gastrointestinal immune system: does highly active antiretroviral therapy restore gut immunity?

CT Costiniuk, JB Angel - Mucosal immunology, 2012 - Elsevier
While only partial immune reconstitution in gut-associated lymphoid tissue typically occurs
following initiation of highly active antiretroviral therapy (HAART) in human
immunodeficiency virus (HIV) infection, near-complete immune reconstitution has
occasionally been described. This review highlights findings from studies examining the
effects of HAART and the timing of its initiation on gastrointestinal (GI) CD4+ T-cell recovery.
Its effects on specific CD4+ T-cell subtypes, CD8+ T cells, natural killer cells, and …