Shifts in macrophage cytokine production drive muscle fibrosis

JG Tidball, M Wehling-Henricks - Nature medicine, 2015 - nature.com
JG Tidball, M Wehling-Henricks
Nature medicine, 2015nature.com
Muscle fibrosis after acute injury can be debilitating, but in chronic muscle disease it can be
lethal. A new study reveals that shifts in macrophage phenotype in injured or diseased
muscle can influence whether connective tissue production by fibro/adipogenic precursors
in muscle is beneficial or pathological.
Muscle fibrosis after acute injury can be debilitating, but in chronic muscle disease it can be lethal. A new study reveals that shifts in macrophage phenotype in injured or diseased muscle can influence whether connective tissue production by fibro/adipogenic precursors in muscle is beneficial or pathological.
nature.com