[HTML][HTML] PPAR-α as a key nutritional and environmental sensor for metabolic adaptation

AV Contreras, N Torres, AR Tovar - Advances in nutrition, 2013 - Elsevier
Peroxisome proliferator-activated receptors (PPARs) are transcription factors that belong to
the superfamily of nuclear hormone receptors and regulate the expression of several genes
involved in metabolic processes that are potentially linked to the development of some
diseases such as hyperlipidemia, diabetes, and obesity. One type of PPAR, PPAR-α, is a
transcription factor that regulates the metabolism of lipids, carbohydrates, and amino acids
and is activated by ligands such as polyunsaturated fatty acids and drugs used to treat …