Prognostic utility of cell cycle progression score in men with prostate cancer after primary external beam radiation therapy
SJ Freedland, L Gerber, J Reid, W Welbourn… - International Journal of …, 2013 - Elsevier
Purpose To evaluate the prognostic utility of the cell cycle progression (CCP) score, a RNA
signature based on the average expression level of 31 CCP genes, for predicting
biochemical recurrence (BCR) in men with prostate cancer treated with external beam
radiation therapy (EBRT) as their primary curative therapy. Methods and Materials The CCP
score was derived retrospectively from diagnostic biopsy specimens of men diagnosed with
prostate cancer from 1991 to 2006 (n= 141). All patients were treated with definitive EBRT; …
signature based on the average expression level of 31 CCP genes, for predicting
biochemical recurrence (BCR) in men with prostate cancer treated with external beam
radiation therapy (EBRT) as their primary curative therapy. Methods and Materials The CCP
score was derived retrospectively from diagnostic biopsy specimens of men diagnosed with
prostate cancer from 1991 to 2006 (n= 141). All patients were treated with definitive EBRT; …