Do adenocarcinomas of the prostate with Gleason score (GS)≤ 6 have the potential to metastasize to lymph nodes?

HM Ross, ON Kryvenko, JE Cowan… - The American journal …, 2012 - journals.lww.com
Although rare, there are cases within reported series of men with Gleason score (GS)≤ 6 on
radical prostatectomies that show pelvic lymph node (LN) metastases. However, there are
no studies on whether pelvic LN metastases occur in tumors with GS≤ 6 using the
International Society of Urological Pathology (ISUP) updated GS system. We performed a
search of the radical prostatectomy databases at 4 large academic centers for cases of GS≤
6. Only prostatectomies submitted and embedded in entirety with pelvic LN dissections were …