Proposed origins of pelvic serous carcinoma include the ovary, fallopian tube, and
peritoneum. Prophylactic salpingo-oophorectomies in BRCA+ women have recently
identified the fimbria as a site of origin for early serous carcinoma (tubal intraepithelial
carcinoma or TIC). We explored the relationship of TIC to pelvic serous carcinomas in
consecutive cases with complete adnexal exam (SEE-FIM protocol). Cases positive (group
A) or negative (group B) for endosalpinx (including fimbria) involvement, were subclassified …