Chronic kidney disease (CKD) is a significant public health problem, and recent genetic studies have identified common CKD susceptibility variants. The CKDGen consortium performed a metaanalysis of genome-wide association data in 67,093 Caucasian individuals from 20 populationbased studies to identify new susceptibility loci for reduced renal function, estimated by serum creatinine (eGFRcrea), cystatin C (eGFRcys), and CKD (eGFRcrea< 60 ml/min/1.73 m2; n= 5,807 CKD cases). Follow-up of the 23 genome-wide significant loci (p< 5× 10− 8) in 22,982 replication samples identified 13 novel loci for renal function and CKD (in or near LASS2, GCKR, ALMS1,