Assessment of oxidative stress in patients with sickle cell disease: The glutathione system and the oxidant–antioxidant status
A Gizi, I Papassotiriou, F Apostolakou… - Blood Cells, Molecules …, 2011 - Elsevier
Continuous reactive oxygen species (ROS) production in individuals with sickle cell disease
(SCD) may alter their overall redox status and cause tissue damage. The aim of this study
was to evaluate oxidative stress in patients with SCD using two new assays, FORT (free
oxygen radical test) and FORD (free oxygen radical defense) along with assessment of
glutathione system including superoxide dismutase (SOD), glutathione reductase (GR) and
glutathione peroxidase (GPx) activities, vitamins A, C and E, malondialdehyde (MDA), non …
(SCD) may alter their overall redox status and cause tissue damage. The aim of this study
was to evaluate oxidative stress in patients with SCD using two new assays, FORT (free
oxygen radical test) and FORD (free oxygen radical defense) along with assessment of
glutathione system including superoxide dismutase (SOD), glutathione reductase (GR) and
glutathione peroxidase (GPx) activities, vitamins A, C and E, malondialdehyde (MDA), non …