Double-blind, placebo-controlled rush immunotherapy with a standardized Alternaria extract
M Horst, A Hejjaoui, V Horst, FB Michel… - Journal of allergy and …, 1990 - Elsevier
Specific immunotherapy is ineffective with unstandardized mold extracts. A double-blind,
placebo-controlled study was performed in 24 patients (5 to 56 years of age) only allergic to
Alternaria. The extract was standardized by isoelectric focusing, crossed
immunoelectrophoresis, crossed radioimmunoelectrophoresis, RAST inhibition, and skin
tests and contained allergen Alternaria major allergen a I and antigen B. Thirteen patients
received the active treatment, and 11 received the placebo. Immunotherapy was started by a …
placebo-controlled study was performed in 24 patients (5 to 56 years of age) only allergic to
Alternaria. The extract was standardized by isoelectric focusing, crossed
immunoelectrophoresis, crossed radioimmunoelectrophoresis, RAST inhibition, and skin
tests and contained allergen Alternaria major allergen a I and antigen B. Thirteen patients
received the active treatment, and 11 received the placebo. Immunotherapy was started by a …
