Diagnosis and management of necrotising fasciitis: a multiparametric approach

MS Morgan - Journal of Hospital Infection, 2010 - Elsevier
Necrotising fasciitis (NF) is situated with myositis and myonecrosis at the severe end of a
spectrum of skin and soft tissue infections but is far removed from erisepelas, impetigo and
cellulitis. Inexperienced clinicians are easily misled by the protean manifestations of
infection, especially exotoxin or superantigen mediated consequences from streptococcal
NF. Early clinical suspicion and surgery are key to improving survival, and patients with NF
need integrated multidisciplinary management, adjusted to the infecting organism (s), the …