Improved in vitro antigen-specific antibody synthesis in two patients with common variable immunodeficiency taking an oral cyclooxygenase and lipoxygenase …
JL Ambrus Jr, S Haneiwich, L Chesky… - Journal of allergy and …, 1991 - Elsevier
In the process of performing a previously published study examining B cell function in 16
patients with common variable immunodeficiency (CVI)(J Allergy Clin Immunol 1991; 87:
1138–1149), we noted improved in vitro antibody (Ab) synthesis in a patient, HB, while he
was taking a cyclooxygenase and lipoxygenase inhibitor, ketoprofen. Addition of ketoprofen
in vitro to B cells from patients with CVI resulted in improved proliferation and differentiation
in four of five additional patients with CVI studied. One patient, besides HB, MKB, whose B …
patients with common variable immunodeficiency (CVI)(J Allergy Clin Immunol 1991; 87:
1138–1149), we noted improved in vitro antibody (Ab) synthesis in a patient, HB, while he
was taking a cyclooxygenase and lipoxygenase inhibitor, ketoprofen. Addition of ketoprofen
in vitro to B cells from patients with CVI resulted in improved proliferation and differentiation
in four of five additional patients with CVI studied. One patient, besides HB, MKB, whose B …