The roles of TGFβ in the tumour microenvironment

M Pickup, S Novitskiy, HL Moses - Nature Reviews Cancer, 2013 - nature.com
Nature Reviews Cancer, 2013nature.com
The influence of the microenvironment on tumour progression is becoming clearer. In this
Review we address the role of an essential signalling pathway, that of transforming growth
factor-β, in the regulation of components of the tumour microenvironment and how this
contributes to tumour progression.
Abstract
The influence of the microenvironment on tumour progression is becoming clearer. In this Review we address the role of an essential signalling pathway, that of transforming growth factor-β, in the regulation of components of the tumour microenvironment and how this contributes to tumour progression.
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