Clinical applications of a peptide-based vaccine for glioblastoma
CW Kanaly, D Ding, AB Heimberger… - Neurosurgery …, 2010 - neurosurgery.theclinics.com
Glioblastoma multiforme (GBM) is the most common primary malignant tumor in the adult
central nervous system. 1 Current therapy for this disease usually includes surgical
resection, radiation, and the administration of temozolomide chemotherapy. It is a
devastating diagnosis, because even with this standard treatment, median survival is less
than 15 months. 2 Additionally, most current therapies are not selective for tumor cells; and
therefore, large amounts of normal healthy tissue are injured as collateral damage while …
central nervous system. 1 Current therapy for this disease usually includes surgical
resection, radiation, and the administration of temozolomide chemotherapy. It is a
devastating diagnosis, because even with this standard treatment, median survival is less
than 15 months. 2 Additionally, most current therapies are not selective for tumor cells; and
therefore, large amounts of normal healthy tissue are injured as collateral damage while …