Molecular phenotypes of acute kidney injury in kidney transplants

KS Famulski, DG de Freitas, C Kreepala… - Journal of the …, 2012 - journals.lww.com
Little is known regarding the molecular phenotype of kidneys with AKI because biopsies are
performed infrequently. However, all kidney transplants experience acute injury, making
early kidney transplants an excellent model of acute injury, provided the absence of
rejection, because donor kidneys should not have CKD, post-transplant biopsies occur
relatively frequently, and follow-up is excellent typically. Here, we used histopathology and
microarrays to compare indication biopsies from 26 transplants with acute injury with 11 …