Background Functional magnetic resonance imaging research suggests that major
depressive disorder (MDD) in both adults and adolescents is marked by aberrant
connectivity of the default mode network (DMN) during resting state. However, emotional
dysregulation is also a key feature of MDD. No studies to date have examined emotion-
related DMN pathology in adolescent depression. Comprehensively understanding the
dynamics of DMN connectivity across brain states in individuals with depression with short …