The glyoxalase system is an enzymatic pathway found in the cytosol of all cells. Recent
research has seen the development of novel anti-tumour and anti-malarial agents targeted
to the glyoxalase system and blood glyoxalase activity values emerge as risk factors for the
development of diabetic complications. A resurgence of interest in this system in biomedical
and pharmaceutical research is at hand. This review explains why. The glyoxalase system is
vital for life support from the earliest stages of embryogenesis, through maturation and …