Allelic Ratio of KRAS Mutations in Pancreatic Cancer
JK Lennerz, A Stenzinger - The oncologist, 2015 - academic.oup.com
The oncologist, 2015•academic.oup.com
KRAS is not simply mutated or wild type in pancreatic ductal adenocarcinoma (PDAC);
actually, it has never been. More than 90% of PDACs carry mutated KRAS alleles; however,
the impact on PDAC biology may vary with the tumor-specific allelic ratio and dosage of
mutated KRAS.
actually, it has never been. More than 90% of PDACs carry mutated KRAS alleles; however,
the impact on PDAC biology may vary with the tumor-specific allelic ratio and dosage of
mutated KRAS.
KRAS is not simply mutated or wild type in pancreatic ductal adenocarcinoma (PDAC); actually, it has never been. More than 90% of PDACs carry mutated KRAS alleles; however, the impact on PDAC biology may vary with the tumor-specific allelic ratio and dosage of mutated KRAS.
Oxford University Press