Thrombocytopenia affects approximately one fourth of neonates admitted to neonatal
intensive care units, and prophylactic platelet transfusions are commonly administered to
reduce bleeding risk. However, there are few evidence-based guidelines to inform clinicians'
decision-making process. Developmental differences in hemostasis and differences in
underlying disease processes make it difficult to apply platelet transfusion practices from
other patient populations to neonates. Thrombocytopenia is a risk factor for common preterm …