[HTML][HTML] The α‐granule proteome: novel proteins in normal and ghost granules in gray platelet syndrome
DM Maynard, HFG Heijnen, WA Gahl… - Journal of thrombosis …, 2010 - Elsevier
See also García Á. Clinical proteomics in platelet research: challenges ahead. This issue, pp
1784–5. Summary Background: Deficiencies in granule‐bound substances in platelets
cause congenital bleeding disorders known as storage pool deficiencies. For disorders such
as gray platelet syndrome (GPS), in which thrombocytopenia, enlarged platelets and a
paucity of α‐granules are observed, only the clinical and histologic states have been
defined. Objectives: In order to understand the molecular defect in GPS, the α‐granule …
1784–5. Summary Background: Deficiencies in granule‐bound substances in platelets
cause congenital bleeding disorders known as storage pool deficiencies. For disorders such
as gray platelet syndrome (GPS), in which thrombocytopenia, enlarged platelets and a
paucity of α‐granules are observed, only the clinical and histologic states have been
defined. Objectives: In order to understand the molecular defect in GPS, the α‐granule …