Increased NFAT5 expression stimulates transcription of Hsp70 in preeclamptic placentas
JK Park, TG Kang, MY Kang, JE Park, IA Cho, JK Shin… - Placenta, 2014 - Elsevier
Objective We investigated the expression of heat shock protein 70 (Hsp70), nuclear factor of
activated T cells 5 (NFAT5), and hypoxia-induced factor-1α (HIF-1α) in the placentas of
normal and preeclamptic pregnancies and in human placental hypoxia models in vitro to
examine the regulatory mechanisms of placental Hsp70 expression. Methods The
expression levels of HIF-1α, NFAT5, and Hsp70 were examined in placental samples from
10 females with preeclampsia and 10 normotensive control patients and in human …
activated T cells 5 (NFAT5), and hypoxia-induced factor-1α (HIF-1α) in the placentas of
normal and preeclamptic pregnancies and in human placental hypoxia models in vitro to
examine the regulatory mechanisms of placental Hsp70 expression. Methods The
expression levels of HIF-1α, NFAT5, and Hsp70 were examined in placental samples from
10 females with preeclampsia and 10 normotensive control patients and in human …