Altered mucosal expression of microRNAs in pediatric patients with inflammatory bowel disease
NJ Béres, Z Kiss, Z Sztupinszki, G Lendvai… - Digestive and Liver …, 2017 - Elsevier
Introduction MicroRNAs (miRs) came recently into focus as promising novel research targets
offering new insights into the pathogenesis of inflammatory bowel diseases (IBD). Aims The
aim of our study was to identify a pediatric IBD (pIBD) characteristic miR profile serving as
potential Crohn's disease (CD) and ulcerative colitis (UC) specific diagnostic pattern and to
further analyze the related target genes. Methods Small RNA sequencing was performed on
inflamed and intact colonic biopsies of CD, and control patients. Selected miRs were further …
offering new insights into the pathogenesis of inflammatory bowel diseases (IBD). Aims The
aim of our study was to identify a pediatric IBD (pIBD) characteristic miR profile serving as
potential Crohn's disease (CD) and ulcerative colitis (UC) specific diagnostic pattern and to
further analyze the related target genes. Methods Small RNA sequencing was performed on
inflamed and intact colonic biopsies of CD, and control patients. Selected miRs were further …