Heart failure with preserved ejection fraction
MM Redfield - New England Journal of Medicine, 2016 - Mass Medical Soc
MM Redfield
New England Journal of Medicine, 2016•Mass Medical SocKey Clinical Points Heart Failure with Preserved Ejection Fraction In patients who have
signs and symptoms of heart failure but a preserved ejection fraction, objective evidence of
abnormal cardiac structure and function should be confirmed by means of
echocardiography, electrocardiography, chest radiography, and measurement of natriuretic
peptide levels. Natriuretic peptide levels may be normal in patients who have heart failure
with a preserved ejection fraction, particularly in obese patients or those with symptoms only …
signs and symptoms of heart failure but a preserved ejection fraction, objective evidence of
abnormal cardiac structure and function should be confirmed by means of
echocardiography, electrocardiography, chest radiography, and measurement of natriuretic
peptide levels. Natriuretic peptide levels may be normal in patients who have heart failure
with a preserved ejection fraction, particularly in obese patients or those with symptoms only …
Key Clinical Points
Heart Failure with Preserved Ejection Fraction
- In patients who have signs and symptoms of heart failure but a preserved ejection fraction, objective evidence of abnormal cardiac structure and function should be confirmed by means of echocardiography, electrocardiography, chest radiography, and measurement of natriuretic peptide levels.
- Natriuretic peptide levels may be normal in patients who have heart failure with a preserved ejection fraction, particularly in obese patients or those with symptoms only on exertion.
- Right heart catheterization may be required in patients in whom there is indeterminate noninvasive testing or evidence of pulmonary hypertension.
- Medications that improve outcomes in patients who have heart failure with a reduced ejection fraction have not been shown to be of benefit in those who have heart failure with a preserved ejection fraction.
- Treatment of heart failure with a preserved ejection fraction should include diuretics for volume overload, treatment for cardiovascular and noncardiovascular coexisting conditions, aerobic exercise training to increase exercise tolerance, education regarding self-care, and disease management programs for patients with refractory symptoms or frequent hospitalizations for heart failure.
The New England Journal Of Medicine