Background To the best of our knowledge, the association between COPD and chronic renal
failure (CRF) has never been assessed. Lean mass is frequently reduced in COPD, and the
glomerular filtration rate (GFR) might be depressed in spite of normal serum creatinine
(concealed CRF). We investigated the prevalence and correlates of both concealed and
overt CRF in elderly patients with COPD. Methods We evaluated 356 consecutive elderly
outpatients with COPD enrolled in the Extrapulmonary Consequences of COPD in the …