[HTML][HTML] Gut instincts: thoughts on intestinal epithelial stem cells
C Booth, CS Potten - The Journal of clinical investigation, 2000 - Am Soc Clin Investig
C Booth, CS Potten
The Journal of clinical investigation, 2000•Am Soc Clin InvestigThe mechanism by which a cell commits and proceeds to full differentiation is currently
unknown. However, certain homeobox transcription factors are likely to be involved.
Homeobox genes determine cell fate and general pattern formation in many tissues,
particularly in regard to cephalocaudal patterning, and the homeobox-containing proteins
cdx-1 and cdx-2 appear to regulate epithelial differentiation, possibly by transducing signals
from the underlying mesenchyme.
unknown. However, certain homeobox transcription factors are likely to be involved.
Homeobox genes determine cell fate and general pattern formation in many tissues,
particularly in regard to cephalocaudal patterning, and the homeobox-containing proteins
cdx-1 and cdx-2 appear to regulate epithelial differentiation, possibly by transducing signals
from the underlying mesenchyme.
The mechanism by which a cell commits and proceeds to full differentiation is currently unknown. However, certain homeobox transcription factors are likely to be involved. Homeobox genes determine cell fate and general pattern formation in many tissues, particularly in regard to cephalocaudal patterning, and the homeobox-containing proteins cdx-1 and cdx-2 appear to regulate epithelial differentiation, possibly by transducing signals from the underlying mesenchyme.
The Journal of Clinical Investigation