Surface Proteins and Exotoxins Are Required for the Pathogenesis of Staphylococcus aureus Pneumonia
JB Wardenburg, RJ Patel, O Schneewind - Infection and immunity, 2007 - Am Soc Microbiol
JB Wardenburg, RJ Patel, O Schneewind
Infection and immunity, 2007•Am Soc MicrobiolABSTRACT A model of Staphylococcus aureus-induced pneumonia in adult,
immunocompetent C57BL/6J mice is described. This model closely mimics the clinical and
pathological features of pneumonia in human patients. Using this system, we defined a role
for S. aureus strain Newman surface proteins and secreted exotoxins in pneumonia-related
mortality.
immunocompetent C57BL/6J mice is described. This model closely mimics the clinical and
pathological features of pneumonia in human patients. Using this system, we defined a role
for S. aureus strain Newman surface proteins and secreted exotoxins in pneumonia-related
mortality.
Abstract
A model of Staphylococcus aureus-induced pneumonia in adult, immunocompetent C57BL/6J mice is described. This model closely mimics the clinical and pathological features of pneumonia in human patients. Using this system, we defined a role for S. aureus strain Newman surface proteins and secreted exotoxins in pneumonia-related mortality.
American Society for Microbiology