[HTML][HTML] Identification of potential biomarkers for clear cell renal cell carcinoma based on microRNA-mRNA pathway relationships
JF Hao, KM Ren, JX Bai, SN Wang… - Journal of cancer …, 2014 - journals.lww.com
Background: MicroRNAs (miRNAs) play important roles in tumor genesis. miRNA
dysregulation has been widely studied and demonstrated in clear cell renal cell carcinoma
(ccRCC). Materials and Methods: We applied a newly proposed method for selecting
miRNAs that discriminate between healthy controls and cancers. We initially extracted
different miRNAs and mRNAs and then selected miRNA-mRNA dysregulation pairs. The
pathways that involved mRNAs were acquired according to the functional enrichment. We …
dysregulation has been widely studied and demonstrated in clear cell renal cell carcinoma
(ccRCC). Materials and Methods: We applied a newly proposed method for selecting
miRNAs that discriminate between healthy controls and cancers. We initially extracted
different miRNAs and mRNAs and then selected miRNA-mRNA dysregulation pairs. The
pathways that involved mRNAs were acquired according to the functional enrichment. We …