Most work describing the histopathology of normal human thymus has focused on pediatric
thymus because of tissue availability and high thymopoietic activity. However, pathologic
examination of the thymus can provide information about immune status that is relevant to
the clinical care of patients of all ages. Understanding age-related changes in the relative
abundance and composition of anatomic compartments within the thymus is critical for
evaluation of the thymus in normal adults and patients with diseases that affect the thymus …