Excess lactate: an index of reversibility of shock in human patients
G Broder, MH Weil - Science, 1964 - science.org
G Broder, MH Weil
Science, 1964•science.org" Excess lactate," an indicator of oxygen debt, has been studied as a metabolic index of
severity of the shock state in human patients. The levels of excess lactate correspond to
severity of circulatory failure, and an excess of more than 4 millimoles per liter
prognosticates a fatal outcome. The validity of this index was confirmed by studies on
experimental hemorrhagic shock in dogs. It provides a parameter for measurement of"
reversibility" and serves as an objective clinical guide.
severity of the shock state in human patients. The levels of excess lactate correspond to
severity of circulatory failure, and an excess of more than 4 millimoles per liter
prognosticates a fatal outcome. The validity of this index was confirmed by studies on
experimental hemorrhagic shock in dogs. It provides a parameter for measurement of"
reversibility" and serves as an objective clinical guide.
"Excess lactate," an indicator of oxygen debt, has been studied as a metabolic index of severity of the shock state in human patients. The levels of excess lactate correspond to severity of circulatory failure, and an excess of more than 4 millimoles per liter prognosticates a fatal outcome. The validity of this index was confirmed by studies on experimental hemorrhagic shock in dogs. It provides a parameter for measurement of "reversibility" and serves as an objective clinical guide.
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