Na+ channel function, regulation, structure, trafficking and sequestration

Y Chen‐Izu, RM Shaw, GS Pitt… - The Journal of …, 2015 - Wiley Online Library
The Journal of physiology, 2015Wiley Online Library
This paper is the second of a series of three reviews published in this issue resulting from
the University of California Davis Cardiovascular Symposium 2014: Systems approach to
understanding cardiac excitation–contraction coupling and arrhythmias: Na+ channel and
Na+ transport. The goal of the symposium was to bring together experts in the field to
discuss points of consensus and controversy on the topic of sodium in the heart. The present
review focuses on Na+ channel function and regulation, Na+ channel structure and function …
Abstract
This paper is the second of a series of three reviews published in this issue resulting from the University of California Davis Cardiovascular Symposium 2014: Systems approach to understanding cardiac excitation–contraction coupling and arrhythmias: Na+ channel and Na+ transport. The goal of the symposium was to bring together experts in the field to discuss points of consensus and controversy on the topic of sodium in the heart. The present review focuses on Na+ channel function and regulation, Na+ channel structure and function, and Na+ channel trafficking, sequestration and complexing.
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