MiR-502-5p inhibits IL-1β-induced chondrocyte injury by targeting TRAF2
G Zhang, Y Sun, Y Wang, R Liu, Y Bao, Q Li - Cellular immunology, 2016 - Elsevier
Osteoarthritis (OA) is characterized by articular cartilage degradation and joint inflammation.
MicroRNAs have been proven to play an important role in the regulation of chondrogenesis.
The aim of the present study was to investigate the effect of miR-502-5p in OA. The results
showed that miR-502-5p levels were significantly down-regulated in OA articular tissues and
IL-1β-induced chondrocytes compared with control groups. MiR-502-5p overexpression
inhibited IL-1β-induced reduction in cell viability and increase in cell apoptosis, and …
MicroRNAs have been proven to play an important role in the regulation of chondrogenesis.
The aim of the present study was to investigate the effect of miR-502-5p in OA. The results
showed that miR-502-5p levels were significantly down-regulated in OA articular tissues and
IL-1β-induced chondrocytes compared with control groups. MiR-502-5p overexpression
inhibited IL-1β-induced reduction in cell viability and increase in cell apoptosis, and …