TGF-β and osteoarthritis—the good and the bad

JR Bush, F Beier - Nature medicine, 2013 - nature.com
JR Bush, F Beier
Nature medicine, 2013nature.com
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Blockage of transforming growth factor-β (TGF-β) signaling in subchondral bone after acute injury in rodents prevents aberrant bone remodeling and cartilage degeneration, suggesting that TGF-β signaling in bone may initiate osteoarthritis in some cases (pages 704–712).
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