[HTML][HTML] The threshold shift paradigm of obesity: evidence from surgically induced weight loss
E Ferrannini, M Rosenbaum, RL Leibel - The American journal of clinical …, 2014 - Elsevier
Background: The high prevalence of obesity has called attention to the near-intractable
problem of sustained weight reduction and its underlying mechanisms. With diet-induced
weight loss, achieved body weight is closely related to initial body weight. Objective: The
objective was to compare the relation between initial and achieved body mass index (BMI)
in patients treated with diet-induced weight loss or bariatric surgery. Design: We analyzed
data from a cohort of 223 healthy individuals who lost a mean (±SD) of 5±3 kg body weight …
problem of sustained weight reduction and its underlying mechanisms. With diet-induced
weight loss, achieved body weight is closely related to initial body weight. Objective: The
objective was to compare the relation between initial and achieved body mass index (BMI)
in patients treated with diet-induced weight loss or bariatric surgery. Design: We analyzed
data from a cohort of 223 healthy individuals who lost a mean (±SD) of 5±3 kg body weight …