Comparative physiogenomic analyses of weight loss in response to 2 modes of bariatric surgery: demonstration with candidate neuropsychiatric and cardiometabolic …
RL Seip, P Papasavas, A Stone, S Thompson… - Surgery for Obesity and …, 2016 - Elsevier
Background Surgical weight loss response is variable, with suboptimal outcomes in some
patients. We hypothesized that genetic biomarkers may be related to weight change.
Methods We tested 330 single nucleotide polymorphisms (SNPs) in genes relevant to
metabolic regulation in 161 patients whose decrease in body mass index (BMI), 1 year after
laparoscopic adjustable gastric banding (LAGB) or Roux-en-Y gastric bypass (RYGB), was
small (lowest quartile response) or large (highest quartile response). LAGB patients whose …
patients. We hypothesized that genetic biomarkers may be related to weight change.
Methods We tested 330 single nucleotide polymorphisms (SNPs) in genes relevant to
metabolic regulation in 161 patients whose decrease in body mass index (BMI), 1 year after
laparoscopic adjustable gastric banding (LAGB) or Roux-en-Y gastric bypass (RYGB), was
small (lowest quartile response) or large (highest quartile response). LAGB patients whose …
