Effect of human papillomavirus on patterns of distant metastatic failure in oropharyngeal squamous cell carcinoma treated with chemoradiotherapy
SJ Trosman, SA Koyfman, MC Ward… - … –Head & Neck …, 2015 - jamanetwork.com
Importance Important differences exist in the pattern and timing of distant metastases
between human papillomavirus–initiated (HPV+) and HPV− oropharyngeal squamous cell
carcinoma (OPSCC). However, our understanding of the natural history of distant
metastases in HPV+ OPSCC and its implications for surveillance is limited. Objective To
investigate the rate, pattern, and timing of distant metastases in advanced-stage OPSCC
treated definitively with concomitant chemoradiotherapy. Design, Setting, and Participants In …
between human papillomavirus–initiated (HPV+) and HPV− oropharyngeal squamous cell
carcinoma (OPSCC). However, our understanding of the natural history of distant
metastases in HPV+ OPSCC and its implications for surveillance is limited. Objective To
investigate the rate, pattern, and timing of distant metastases in advanced-stage OPSCC
treated definitively with concomitant chemoradiotherapy. Design, Setting, and Participants In …
