[HTML][HTML] Role of NK, NKT cells and macrophages in liver transplantation
R Fahrner, F Dondorf, M Ardelt… - World journal of …, 2016 - ncbi.nlm.nih.gov
R Fahrner, F Dondorf, M Ardelt, U Settmacher, F Rauchfuss
World journal of gastroenterology, 2016•ncbi.nlm.nih.govLiver transplantation has become the treatment of choice for acute or chronic liver disease.
Because the liver acts as an innate immunity-dominant organ, there are immunological
differences between the liver and other organs. The specific features of hepatic natural killer
(NK), NKT and Kupffer cells and their role in the mechanism of liver transplant rejection,
tolerance and hepatic ischemia-reperfusion injury are discussed in this review.
Because the liver acts as an innate immunity-dominant organ, there are immunological
differences between the liver and other organs. The specific features of hepatic natural killer
(NK), NKT and Kupffer cells and their role in the mechanism of liver transplant rejection,
tolerance and hepatic ischemia-reperfusion injury are discussed in this review.
Abstract
Liver transplantation has become the treatment of choice for acute or chronic liver disease. Because the liver acts as an innate immunity-dominant organ, there are immunological differences between the liver and other organs. The specific features of hepatic natural killer (NK), NKT and Kupffer cells and their role in the mechanism of liver transplant rejection, tolerance and hepatic ischemia-reperfusion injury are discussed in this review.
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