Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients

X Li, GA Hawkins, EJ Ampleford, WC Moore… - Journal of allergy and …, 2013 - Elsevier
Background Recent meta-analyses of genome-wide association studies in general
populations of European descent have identified 28 loci for lung function. Objective We
sought to identify novel lung function loci specifically for asthma and to confirm lung function
loci identified in general populations. Methods Genome-wide association studies of lung
function (percent predicted FEV 1 [ppFEV 1], percent predicted forced vital capacity, and
FEV 1/forced vital capacity ratio) were performed in 4 white populations of European …