Relation of the pH of nasal secretions in situ to the activity of lysozyme: report of a case of experimentally induced allergic rhinitis

ND FABRICANT - Archives of Otolaryngology, 1945 - jamanetwork.com
In previous communications I 1 reported that thep H of nasal secretions in situ in clinically
normal nasal passages ranges from approximately 5.5 to 6.5 and that these secretions
become alkaline during acute rhinitis and acute rhinosinusitis and during the more active
phases of allergic rhinitis. In the light of Meyer's 2 recent accomplishment—increasing the
activity of lysozyme from eight to two hundred and fifty times by the addition of a minute
amount of biotin—the relationship of thep H of nasal secretions in situ to the activity of …