Associations Between Mutations and Histologic Patterns of Mucin in Lung Adenocarcinoma: Invasive Mucinous Pattern and Extracellular Mucin Are Associated With …
K Kadota, YC Yeh, SP D'Angelo… - The American journal …, 2014 - journals.lww.com
Multiple reports indicate that epidermal growth factor receptor (EGFR) mutations are
associated with lepidic-pattern lung adenocarcinoma and that KRAS mutations are
associated with invasive mucinous adenocarcinoma. We sought to investigate the
association between EGFR and KRAS mutations and specific morphologic characteristics,
such as predominant histologic subtype and mucinous features. Clinical data for 864
patients with resected lung adenocarcinoma that underwent molecular testing for EGFR and …
associated with lepidic-pattern lung adenocarcinoma and that KRAS mutations are
associated with invasive mucinous adenocarcinoma. We sought to investigate the
association between EGFR and KRAS mutations and specific morphologic characteristics,
such as predominant histologic subtype and mucinous features. Clinical data for 864
patients with resected lung adenocarcinoma that underwent molecular testing for EGFR and …
