Brown, beige, and white: the new color code of fat and its pharmacological implications
A Pfeifer, LS Hoffmann - Annual review of pharmacology and …, 2015 - annualreviews.org
Brown adipose tissue (BAT) was previously regarded as a special type of fat relevant only
for defending hibernating animals and newborns against a cold environment. Recently, BAT
has received considerable attention following its (re) discovery in humans. Using glucose
tracers, multiple laboratories independently found metabolically active BAT in adults. The
enormous metabolic powers of BAT in animal models could make it an attractive target for
antiobesity therapies in humans. Here, we review the present knowledge on the role of BAT …
for defending hibernating animals and newborns against a cold environment. Recently, BAT
has received considerable attention following its (re) discovery in humans. Using glucose
tracers, multiple laboratories independently found metabolically active BAT in adults. The
enormous metabolic powers of BAT in animal models could make it an attractive target for
antiobesity therapies in humans. Here, we review the present knowledge on the role of BAT …
