[HTML][HTML] Molecular cloning of mouse amino acid transport system B0, a neutral amino acid transporter related to Hartnup disorder
A Bröer, K Klingel, S Kowalczuk, JEJ Rasko… - Journal of Biological …, 2004 - ASBMB
Resorption of amino acids in kidney and intestine is mediated by transporters, which prefer
groups of amino acids with similar physico-chemical properties. It is generally assumed that
most neutral amino acids are transported across the apical membrane of epithelial cells by
system B 0. Here we have characterized a novel member of the Na+-dependent
neurotransmitter transporter family (B 0 AT1) isolated from mouse kidney, which shows all
properties of system B 0. Flux experiments showed that the transporter is Na+-dependent …
groups of amino acids with similar physico-chemical properties. It is generally assumed that
most neutral amino acids are transported across the apical membrane of epithelial cells by
system B 0. Here we have characterized a novel member of the Na+-dependent
neurotransmitter transporter family (B 0 AT1) isolated from mouse kidney, which shows all
properties of system B 0. Flux experiments showed that the transporter is Na+-dependent …