Reversal of cirrhosis: evidence-based medicine?
VJ Desmet, T Roskams - Gastroenterology, 2003 - gastrojournal.org
The term “reversal”(like “regression”) is intrinsically ambiguous. Reversal (and regression)
can be minimal, partial, substantial, or complete; all variants are covered by the term
reversal (or regression). Poynard et al. 1 define reversal of cirrhosis as “a change in fibrosis
score based on the biopsy sample”(pg. 1304 and 1312). This is a questionable definition of
reversal of cirrhosis. Cirrhosis implies more than just fibrosis, but in addition nodular
parenchymal regeneration and development of intrahepatic porto-hepatic and arteriovenous …
can be minimal, partial, substantial, or complete; all variants are covered by the term
reversal (or regression). Poynard et al. 1 define reversal of cirrhosis as “a change in fibrosis
score based on the biopsy sample”(pg. 1304 and 1312). This is a questionable definition of
reversal of cirrhosis. Cirrhosis implies more than just fibrosis, but in addition nodular
parenchymal regeneration and development of intrahepatic porto-hepatic and arteriovenous …