Persistent elevation of inflammatory cytokines predicts a poor outcome in ARDS: plasma IL-1β and IL-6 levels are consistent and efficient predictors of outcome over …

GU Meduri, S Headley, G Kohler, F Stentz, E Tolley… - Chest, 1995 - Elsevier
Background Inflammatory cytokines have been related to the development of adult
respiratory distress syndrome (ARDS), shock, and multiple organ dysfunction syndrome
(MODS). We tested the hypothesis that unfavorable outcome in patients with ARDS is
related to the presence of a persistent inflammatory response. For this purpose, we
evaluated the behavior of inflammatory cytokines during progression of ARDS and the
relationship of plasma inflammatory cytokines with clinical variables and outcome. Methods …