Water is the most abundant molecule in any cell. Specialized membrane channel, proteins
called aquaporins, facilitate water transport across cell membranes. At least seven
aquaporins (AQP): 1, 2, 3, 4, 6, 7, and 11 are expressed in the kidneys. Aquaporins play a
role in both the short-term and long-term regulation of water balance as well as in the
pathophysiology of water balance disorders. Aquaporin is composed of a single peptide
chain consisting of approximately 270 amino acids. Inherited central and nephrogenic …