Impact of age, gender, and race on circulating γδ T cells
C Cairo, CL Armstrong, JS Cummings, CO Deetz… - Human immunology, 2010 - Elsevier
A major subset of human peripheral blood γδ T cells expresses the Vγ2Vδ2 T cell receptor
and responds to malignant or infectious diseases. We noted significant differences in the
numbers of Vγ2Vδ2 T cells in blood samples from healthy Caucasian CA or African
American (AA) donors. On average, CA donors had 3.71%±4.37% Vδ2 cells (as a
percentage of total lymphocytes) compared with 1.18%±2.14% Vδ2 cells for AA donors (p<
0.0001). Age and race had the greatest impact on Vδ2 cell levels; the effect of age was …
and responds to malignant or infectious diseases. We noted significant differences in the
numbers of Vγ2Vδ2 T cells in blood samples from healthy Caucasian CA or African
American (AA) donors. On average, CA donors had 3.71%±4.37% Vδ2 cells (as a
percentage of total lymphocytes) compared with 1.18%±2.14% Vδ2 cells for AA donors (p<
0.0001). Age and race had the greatest impact on Vδ2 cell levels; the effect of age was …
