Prevalence of dystrophin-positive fibers in 85 Duchenne muscular dystrophy patients
M Fanin, GA Danieli, L Vitiello, L Senter… - Neuromuscular …, 1992 - Elsevier
The prevalence of dystrophin-positive fibers in Duchenne muscular dystrophy (DMD) muscle
was estimated by direct counting on immunostained sections in a series of biopsy
specimens from 85 patients, 42 of which were also screened for intragenic deletions by
cDNA probes. Dystrophin-positive fibres are normotrophic and occur in muscle sections at a
frequency between 0.01 and 6.81%. Frequencies over 1% were found only in patients older
than 6 yr. The prevalence of dystrophin-positive fibers is about the same in patients with …
was estimated by direct counting on immunostained sections in a series of biopsy
specimens from 85 patients, 42 of which were also screened for intragenic deletions by
cDNA probes. Dystrophin-positive fibres are normotrophic and occur in muscle sections at a
frequency between 0.01 and 6.81%. Frequencies over 1% were found only in patients older
than 6 yr. The prevalence of dystrophin-positive fibers is about the same in patients with …
