[HTML][HTML] Dynamic developmental elaboration of N-linked glycan complexity in the Drosophila melanogaster embryo
The structural diversity of glycoprotein N-linked oligosaccharides is determined by the
expression and regulation of glycosyltransferase activities and by the availability of the
appropriate acceptor/donor substrates. Cells in different tissues and in different
developmental stages utilize these control points to manifest unique glycan expression
patterns in response to their surroundings. The activity of a Toll-like receptor, called
Tollo/Toll-8, induces a pattern of incompletely defined, but neural specific, glycan expression …
expression and regulation of glycosyltransferase activities and by the availability of the
appropriate acceptor/donor substrates. Cells in different tissues and in different
developmental stages utilize these control points to manifest unique glycan expression
patterns in response to their surroundings. The activity of a Toll-like receptor, called
Tollo/Toll-8, induces a pattern of incompletely defined, but neural specific, glycan expression …